25. Clear cell carcinoma Clear cell ovarian tumors are part of the surface epithelial tumor group of ovarian cancers, Accounting for 6% of these cancers. Polypoid masses that protrude into the cyst. On microscopic examination, composed of cells with clear cytoplasm (that contains glycogen) Hob nail cells. The pattern may be glandular, papillary. Ovarian Cancer Valerie Waddell, MD Assistant Professor, Clinical - Nt k /Btti iNew tumor mar k ers/Better imaging Microsoft PowerPoint - Ovarian Cancer Final - Handout.ppt [Compatibility Mode] Author: free42 Created Date: 3/25/2014 2:01:10 PM. Introduction Ovarian cancer accounts for 3-4% of cancer in women And is the fourth most frequent cause of cancer-related death in females in the United States In the year 2005, an estimated 22,000 new ovarian cancer cases were diagnosed in the United States and 16,000 patients succumbed to the disease. Ovarian cancer is the second most common. OVARIAN CANCER - OVARIAN CANCER Di Wen, M.D.,Ph.D Definition Ovarian tumors may arise at any age, but are commonest between 30 and 60. 1.Ovarian tumors are particularly liable to | PowerPoint PPT presentation | free to vie Imaging strategy for early ovarian cancer: characterization of adnexal masses with conventional and advanced imaging techniques. Radiographics, 32(6), pp.1751-1773 36. • Among women with ovarian disorders, CT has been used primarily in patients with ovarian malignancies, either to assess disease extent prior to surgery or as a substitute for.
BOTs form a separate entity within the group of ovarian tumours. BOTs can be divided according to their epithelialcharacteristics as serous (50%),mucinous (46%),and mixed, endometrioid, clear cell, or Brennertumors (3.9%). Serous BOTs are bilateral in 30%of patients and can be associated with extraovarian lesions (so-called implants) in 35% BENIGN OVARIAN TUMORS Dr. Mashael Al-Shebaili Asst. Prof. & Consultant Ob/Gyn Dept. Ovaries are normally not palpable in pre-menarche, and after the menopause In the - PowerPoint PPT presentation. Number of Views: 1049. Avg rating:3.0/5.0. Slides: 17 Ovarian tumors are relatively common and account for ~6% of female malignancies. This article focuses on the general classification of ovarian tumors. For specific tumor features, please refer to the relevant subarticles. Pathology Subtypes Pr..
. Ovarian tumors are classified as epithelial tumors, germ cell tumors, sex cord-stromal cell tumors, and metastatic tumors on the basis of tumor origin (, Table 1) (, 1).Although ovarian tumors have similar clinical and radiologic features, predominant or specific imaging features may be present in some types of ovarian tumors 1 Ovarian tumor - Benign Ovarian tumors and Borderline malignant tumors - - A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 6bd6cd-YzZi Save Save Lecture 23- Ovarian Tumours.ppt For Later. 0 ratings 0% found this document useful (0 votes) 94 views 89 pages. Lecture 23 - Ovarian Tumours. Original Title: CA 15-3 PRIMARY MALIGNANT OVARIAN TUMORS IMAGING CHARACTERISTICS • Local findings:. OVARIAN CANCER Staging & FU Ovarian Ca Pre treatment staging of ovarian cancer • CT (ACR 9) MR (ACR 7) PET (ACR 4) US (ACR 3) Rule out recurrence ovarian cancer • CT abd/pelvis (ACR 9) PET-CT (ACR 8) CT c/a/p (ACR 6) MR (ACR 4) US (ACR 3) Ovarian Carcinoma Bilateral ovarian tumors and peritonea CT and MR imaging are most useful in assessing and planning treatment for more advanced ovarian cancer. MR imaging is particularly useful in evaluating tumor extension into the uterus, bladder, rectum, or pelvic sidewall and in determining whether tumors can be optimally debulked (, 54). The reported overall staging accuracy of MR imaging is 75.
Ovarian Cancer Early Detection, Diagnosis, and Staging cancer.org | 1.800.227.2345 Imaging tests Doctors use imaging tests to take pictures of the inside of your body.€Imaging tests can show whether a pelvic mass is present, but they cannot confirm that the mass is a cancer. These tests are also useful if your doctor is looking to see if. Introduction. Ovarian neoplasms are uncommon in the pediatric population, with an estimated incidence of 2.6 cases per 100,000 girls per year ().Ovarian malignancy in children and adolescents is reported in 10%-20% of all ovarian masses or neoplasms and comprises aproximately 1%-2% of all childhood malignancies (2-4).In a series of 1037 malignant ovarian tumors (), the age-adjusted. with ovarian cancer, the overall 5-year survival rate has changed little (1-4). Ovarian tumors can be categorized as epithe-lial, germ cell, sex cord-stromal, or metastatic. Epithelial tumors are the most common histo-pathologic type of malignant ovarian tumor (85% of cases) (Fig 1) (5,6). Subtypes of epithelial tu-mors include serous.
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Ovarian teratomas include mature cystic teratomas (dermoid cysts), immature teratomas, and monodermal teratomas (eg, struma ovarii, carcinoid tumors, neural tumors). Most mature cystic teratomas can be diagnosed at ultrasonography (US) but may have a variety of appearances, characterized by echogenic sebaceous material and calcification This tumor is also one of the primary peritoneal malignancies. It occurs exclusively in women. This tumor is histologically identical to malignant ovarian surface epithelial tumors. It was once thought to be very rare, but now almost one third of tumors previously diagnosed as ovarian cancer are diagnosed as primary peritoneal serous carcinoma Dr. Balachandran is an Assistant Professor and Dr. Iyer is an Associate Professor, Department of Diagnostic Imaging, UT MD Anderson Cancer Center, Houston, TX.. Ovarian cancer is the second most common gynecologic malignancy and is the fifth leading cause of cancer death in women. 1 Nearly 75% of women with ovarian cancer present with advanced stage disease, which is associated with a poor. Ovarian Teratomas: Tumor Types and Imag-ing Characteristics1 LEARNING OBJECTIVES FOR TEST 6 After reading this article and taking the test, the reader will be able to: Enumerate the most common types of ovarian teratomas. Discuss the histo-logic characteristics and speciﬁc US, CT, and MR imaging fea-tures of the various types of ovarian tera. The Ovarian-Adnexal Reporting and Data System (O-RADS) US risk stratification and management system is designed to provide consistent interpretations, to decrease or eliminate ambiguity in US reports resulting in a higher probability of accuracy in assigning risk of malignancy to ovarian and other adnexal masses, and to provide a management recommendation for each risk category
Identifying Ovarian Tumors at High Risk for Ovarian Cancer - Identifying Ovarian Tumors at High Risk for Ovarian Cancer Frederick R. Ueland, M.D. Associate Professor Gynecologic Oncology Vice Chairman, The PowerPoint PPT presentation: Imaging of Renal Tumors is the property of its rightful owner Ovarian cancer is the second most common of all gynecologic malignancies. It is the leading cause of death in this category of diseases, frequently presenting as a complex cystic mass. The finding of an adnexal cyst causes considerable anxiety in women due to the fear of malignancy MRI in ovarian cancer REVIEW At present, more than 75% of patients with ovarian cancer are diagnosed in an advanced tumor stage. This is mainly owing to a long period with unspecific symptoms; ovarian can-cer remains the most deadly entity among all female reproductive system cancers. Overall the disease ranks fifth among the most lethal can mates by the American Cancer Society, ovarian cancer accounted for 3% of new cases of female malignancies and 5% of cancer-related deaths in 2009 in the United States . Imaging, especially ultrasound and CT, has become a critical part of the evaluation of patients with ovarian cancer. As for many other malignancies, the role o
Ovarian dermoid cyst and mature cystic ovarian teratoma are terms often used interchangeably to refer to the most common ovarian neoplasm.These slow-growing tumors contain elements from multiple germ cell layers and are best assessed with ultrasound Sonography and Ovarian Tumors. Professor Galal Lotfi. Obstetrics & Gynecology. Suez Canal University. The incidence of ovarian carcinoma has increased and - A free PowerPoint PPT presentation (displayed as a Flash slide show) on PowerShow.com - id: 1d8643-ZDc1 Epithelial Ovarian Cancer Page 5 of 10 Disclaimer: This algorithm has been developed for MD Anderson using a multidisciplinary approach considering circumstances particular to MD Anderson ' s specific patient population, services and structure Ovarian Cancer Valerie Waddell, MD Assistant Professor, Clinical General Division of Obstetrics and Gynecology The Ohio State University Wexner Medical Center Objectives • Define symptoms and risk factors for ovarian cancer • Ri th l tiReview the evaluation for an adnexal mass • Discuss the diagnosis and management of ovarian cancer.
Types of Ovarian Cancer. There are three main types of ovarian tumors: Epithelial tumors - derived from the cells on the surface of the ovary. This is the most common form of ovarian cancer and occurs primarily in adults. Germ cell tumors - derived from the egg producing cells within the body of the ovary. This occurs primarily in children and. The International Ovarian Tumour Analysis criteria - IOTA • Preoperative classification system for ovarian tumours consisting of: - 5 features typical for benign tumours (B-features). - 5 features typical for malignant tumours (M-Features). • Based on which of the B-features and M-features that apply Ovarian Tumors Who Cares? Surgical costs exceed $5,000,000,000 annually 144 million women in USA - 5-10% will undergo a surgical procedure for a suspected ovarian neoplasm during their lifetime 30 million women over age 50 - 17% develop cystic ovarian tumors - 2 million have persistent tumors Borderline serous tumors account for 10-15% of all ovarian serous tumors. Most studies show that on average, borderline serous tumors are diagnosed in the fifth decade of life. 8, 10, 11 Up to one-third of these tumors are bilateral. Treatment is surgical. Reported 5-year survival rates are 70-95%
Ovarian torsion, also sometimes termed adnexal torsion or tubo-ovarian torsion, refers to rotation of the ovary and portion of the fallopian tube supplying the vascular pedicle.. It can be intermittent or sustained and results in venous, arterial and lymphatic stasis. It is a gynecological emergency and requires urgent surgical intervention to prevent ovarian necrosis PET/CT is limited in characterizing ovarian masses, but it is helpful in staging ovarian cancer and for detecting recurrent disease, particularly in the setting of negative imaging findings but increasing tumor markers [52-59]. Peritoneal tumor deposits are often less than 1 cm, a size at which PET has limited spatial resolution Ovarian cancer Pelvic or abdominal pain, abdominal fullness and pressure, bloating, difficulty eating, early satiety, increased abdominal size, indigestion, dyspareunia, urinary urgency or frequency Epithelial ovarian cancer is the commonest cause of gynaecological cancer-associated death. The disease typically presents in postmenopausal women, with a few months of abdominal pain and distension. Most women have advanced disease (International Federation of Gynecology and Obstetrics [FIGO] stage III), for which the standard of care remains surgery and platinum-based cytotoxic chemotherapy
[1-3] In some cases, the dominant mucinous component of the lesion can be as large as 50 cm. This report aims to describe the case of a benign mixed Brenner tumor and mucinous cystadenoma with a dominant Brenner tumor component and to review the imaging features of a combined ovarian lesion rarely identified on imaging Lin HW, Tu YY, Lin SY, et al. Risk of ovarian cancer in women with pelvic inflammatory disease: a population-based study. Lancet Oncol. 2011 Sep. 12(9):900-4. . Coakley FV. Staging ovarian cancer: role of imaging. Radiol Clin North Am. 2002 May. 40 (3):609-36. . Zeppernick F, Meinhold-Heerlein I Ovarian cancer stages range from stage I (1) through IV (4). As a rule, the lower the number, the less the cancer has spread. A higher number, such as stage IV, means cancer has spread more. Although each person's cancer experience is unique, cancers with similar stages tend to have a similar outlook and are often treated in much the same way
PowerPoint is the world's most popular presentation software which can let you create professional Ovarian Cancer Screening and Diagnosis powerpoint presentation easily and in no time. This helps you give your presentation on Ovarian Cancer Screening and Diagnosis in a conference, a school lecture, a business proposal, in a webinar and business and professional representations 48. Low RN, Duggan B, Barone RM, Saleh F, Song SY. Treated ovarian cancer: MR imaging, laparotomy reassessment, and serum CA-125 values compared with clinical outcome at 1 year. Radiology 2005; 235:918-926 [Google Scholar Abstract. Epithelial ovarian cancer is the most common ovarian malignancy. CA125, the glycoprotein defined by the antibody OC 125, is the most important clinical marker for the diagnosis, treatment and follow-up of epithelial ovarian cancer. However, like most tumor markers, it is neither wholly specific nor sensitive for the disease Ovarian hyperstimulation syndrome (OHSS) is a complication of ovarian stimulation treatment (ovarian induction therapy) for in vitro fertilisation.Rarely, it may also occur spontaneously in pregnancy (see below). It consists of ovarian enlargement with extravascular accumulation of fluid leading to variable weight gain, ascites, pleural effusions , intravascular volume depletion and oliguria
Renal Tumors: 10 16% Lifetime Risk. Type 2 Papillary Renal Cancer (characteristic PPT. Presentation Summary : Renal tumors: 10-16% lifetime risk. Type 2 papillary renal cancer (characteristic histopathology) Tubulo-papillary renal cell carcinoma Three sorts of ovarian tumors are: Epithelial cell tumors- begin from the cells on the surface of the ovaries. These are the most well-known sort of ovarian tumors. Germ cell tumors- begin in the cells that create the eggs. They can either be favorable or malignant. Stromal tumors- start in the cells that produce female hormone
The lifetime ovarian cancer risk for women with a BRCA1 mutation is estimated to be between 35% and 70%. This means that if 100 women had a BRCA1 mutation, between 35 and 70 of them would get ovarian cancer. For women with BRCA2 mutations the risk has been estimated to be between 10% and 30% by age 70. These mutations also increase the risks. The improved detection of ovarian cancer at the earliest stages of development would confer a significant benefit in the therapeutic efficacy and overall survival associated with this devastating disease. The inadequate performance of currently used imaging modalities and the CA 125 biomarker test h Malignant lesions of the ovaries include primary lesions arising from normal structures within the ovary and secondary lesions from cancers arising elsewhere in the body. Primary lesions include epithelial ovarian carcinoma (70% of all ovarian malignancies), germ-cell tumors, sex-cord stromal tumors, and other more rare types Some types of tumor (e.g., endometriomas, mature cystic teratomas (dermoid cysts), hydro- pyo- and hemato-salpinx, peritoneal pseudocysts, paraovarian cysts, hemorrhagic corpus luteum cysts, myomas, abscesses and ovarian fibromas, thecomas, and Brenner tumours) may manifest a characteristic appearance at grayscale imaging. 4, 9, 10, 56 - 67.
Targeted Therapy for Ovarian Cancer. Targeted therapy is a type of cancer treatment that uses drugs to identify and attack cancer cells while doing little damage to normal cells. These therapies attack the cancer cells' inner workings − the programming that makes them different from normal, healthy cells. Each type of targeted therapy works. Kinetics of HE4 and CA125 as prognosis biomarkers during neoadjuvant chemotherapy in advanced epithelial ovarian cancer. Ovarian cancer (OC) is considered the most lethal gynecological cancer, of which more than 65% cases are diagnosed in advanced stages, requiring platinum-based neoadjuvant chemotherapy (NACT)
Ovarian granulosa cell tumors (GCTs) are divided into adult GCT (AGCT) and juvenile GCT (JGCT). The AGCT is more common type, conversely, less than 5% of tumors are the JGCT and occur in mainly premenarchal girls and in women younger than 30 years. Although JGCT have different histologic features compared to AGCT, the two types have similar imaging features because they have similar gross. Peritoneal Carcinomatosis Histology is a serous carcinoma Ovarian primary not detectable Can occur in women s/p oophorectomy Small deposits of tumor can be seen on ovary surfaces Some women have BRCA 1 mutations Treatment similar to ovarian cancer Surgical debulking Followed by systemic chemotherapy Survival Similar to ovarian cancer at. E pidemiology. Borderline ovarian tumors comprise about 15%-20% of all epithelial ovarian malignancies [2, 3] with an incidence of 1.8-4.8 per 100,000 women per year [3-5].BOTs differ significantly from ovarian carcinomas with regard to percentile distribution of tumor histotypes, lower FIGO stage, excellent overall prognosis, younger age distribution, higher infertility rate, and a.
Introduction. Cervical cancer is the third most common gynecologic malignancy in the United States. In 2011, 12,710 new cases and 4290 deaths 1 are expected in the United States. However, in the underdeveloped world where screening remains underutilized, cervical cancer is the second most common cancer in women, with 275,000 deaths worldwide in 2002. 2 In the past 50 years, there has been a. In the United States, ovarian cancer is the eighth most common cancer among women, according to the Centers for Disease Control and Prevention (CDC). While there are more than 30 types of ovarian cancer, all begin in one or both ovaries, or in the nearby fallopian tubes or peritoneum (the tissue that covers organs in the abdomen) Struma ovarii (SO) is defined as an ovarian teratoma that is composed predominantly (over 50%) or entirely of thyroid tissue. [ 1] It may demonstrate pathologic features that can be seen in the normal thyroid including benign and malignant changes. [ 2] Although 5-15% of all ovarian teratomas may contain some thyroid tissue; only 2% of these. 1 Introduction. Granulosa cell tumors (GCTs) is an extremely rare, sex cord-stroma tumors constituting only 1% to 2% of all ovarian malignancies. On the basis of age of onset and clinicopathological characteristics, these tumors are subdivided into 2 distinct forms, the adult type (AGCT) and the juvenile type (JGCT), representing 95% and 5% of the tumors, respectively Recurrent Ovarian Cancer is a Chronic Disease Process. For most women who are diagnosed with ovarian cancer, the cancer will recur and the cancer becomes a chronic disease. Over 70% of all women diagnosed with ovarian cancer will have recurrent disease. Good news is that women are . living longer. with . better quality of life . with recurrent.
Ovarian Cancer Risk Factors. 50 years of age or older. Familial factors. Family history of breast, ovarian, or colon cancer ?3x baseline risk. Personal history of breast or colon cancer. Familial cancer syndrome (10%) BRCA (breast cancer) gene mutation. Hereditary nonpolyposis colon cancer (HNPCC) Other potential risk factor In the world of ovarian cancer there have also been significant changes, with universal genetic testing now recommended for all ovarian cancer patients and data showing a myriad of risk reduction options for those at high risk. Recommendation for universal genetic testing for all ovarian cancer patients (SGO 2014 Free Download IMAGING ANATOMY OF FEMALE REPRODUCTIVE SYSTEM PowerPoint Presentation. Low cellularity tumors and mucinous tumors - high ADC Peritoneal implants from ovarian Ca have low ADC. Slide 61-MAGNETIC RESONANCE IMAGING -OVARY T2WI Outer cortex - slightly decreased SI Inner medulla - intermediate to slightly increased signal. Learned from Ovarian Cancer Screening Trials Compared to Society of Radiologists in Ultrasound Guideline but PowerPoint presentation would also be acceptable.1. Discuss the epidemiology of Review the overview and current classification of endometrial cancer.Describe the typical MR imaging appearances of type1 an
• The treatment of epithelial ovarian cancer continues to be combination of surgery and chemotherapy. - Upfront surgery: greater emphasis on complete resection. - Neoadjuvant chemotherapy • Decision to choose the surgical strategy is a multifactorial process with the goal of maximizin Ovarian cysts are fluid-filled sacs or pockets within or on the surface of an ovary. Women have two ovaries — each about the size and shape of an almond — located on each side of the uterus. Eggs (ova) develop and mature in the ovaries and are released in monthly cycles during your childbearing years 2. To identify critical imaging findings in ovarian cancer staging. 3. To discuss imaging pitfalls. Background Ovarian cancer is the fifth most common cause of cancer death in women (1.
Source: American Cancer Society Stage 3 Treatment. Treatment for Stage III ovarian cancer is the same as for Stage II ovarian cancer: hysterectomy and bilateral salpingo-oophorectomy (removal of both ovaries and fallopian tubes), debulking of as much of the tumor as possible, and sampling of lymph nodes and other tissues in the pelvis and abdomen that are suspected of harboring cancer Ovarian cancer can be a frightening diagnosis, with five-year relative survival rates that range from 93% to 19% for epithelial ovarian cancer, depending on the stage when the cancer was found From the available data, there is no accurate way to predict the final pathology of ovarian tumors from laboratory or imaging studies alone. Previous Next: Prognosis in Borderline Ovarian Cancer. Patients with borderline tumors have an excellent overall prognosis. These women have a 60% chance of having stage I disease when diagnosed Type II ovarian tumors: high-grade, aggressive tumors that typically involve both. ovaries. and are diagnosed at an advanced stage. Histologic subtypes include high-grade serous, carcinosarcoma, and undifferentiated. carcinoma. Account for ∼ 90% of. ovarian cancer. deaths. Associated with high levels of Prognosis (survival) for BRCA1/2-related cancer depends on the stage at which the cancer is diagnosed and on the type of mutation; however, studies of survival have revealed conflicting results for individuals with germline BRCA1 or BRCA2 pathogenic variants when compared to controls.Retrospective studies suggest that heterozygosity for a BRCA hereditary pathogenic variant in ovarian cancer. Oral contraceptives offer the added benefit of significantly reducing your risk of ovarian cancer — the risk decreases the longer you take birth control pills. • Surgery : Your doctor may suggest removal of a cyst if it is large, doesn't look like a functional cyst, is growing, or persists through two or three menstrual cycles